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Standard Approach to the Diagnosis of Severe Aplastic Anemia in Pediatrics

• Moderator: Jennifer Rothman, MD
• Speaker: Akiko Shimamura, MD PhD, and Alison A. Bertuch, MD PhD

With an increase in potential therapeutic options for severe aplastic anemia, it is increasing important to differentiate idiopathic or immune mediated aplasia from progressive aplasia associated with inherited bone marrow failure syndromes or hypoplastic MDS. Understanding which screening tests to send, both functional and emerging molecular testing, as well as interpreting ambiguous results, is an ongoing challenge for clinicians when developing a treatment plan for newly diagnosed patients with SAA. This is particularly challenging due to the rarity of the disorder as well as the, sometimes, limited availability of specialized testing in many settings. The goal of this webinar is to review a standardized approach to the diagnosis of SAA and associated conditions developed by the North American Aplastic Anemia Consortium (NAPAAC) as well as discuss benefits and limitations of specialized testing. PHO learners will be provided with a diagnostic framework to approach these challenging patients.

Learning Objectives:

• Identify clinical and laboratory studies that are essential in the diagnosis of severe aplastic anemia
• Distinguish severe aplastic anemia for other causes such as MDS and inherited bone marrow failure syndromes.

Details

Categories: Webinar